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Nano-knife, Precise Breakdown Of Tumor Cells
- Mar 16, 2018 -

In killing tumor cells, how to maximize the protection of surrounding tissues from damage? Recently, in China's people's liberation army general hospital (301) at the international conference on nano knife technology project, the hospital of doctor of vice director of liver and gallbladder surgery yong-liang Chen, a professor at the team with the university of louisville in Kentucky team demonstrated a new technology, nano knife tumor treatment to make these into reality.

The cell membrane of tumor cells perforates under high pressure current, leading to the death of tumor cells.

Tumor ablation is a major advance in the treatment of tumors in the 21st century. It allows many patients who cannot be resected, or who are not able to undergo surgical resection, to be treated effectively. At present, the commonly used techniques include radiofrequency, microwave ablation (thermal ablation) and liquid nitrogen ablation (cold ablation). Despite their advantages, the problem with cold and heat effects is that it is often difficult to avoid damage to surrounding tissues while killing tumor cells.

The nano-knife principle is to allow the cell membrane of tumor cells to be perforated at the nanoscale under the action of high pressure current, leading to the death of tumor cells. Nano ablation therapy under CT guidance 301 hospital radiology department, deputy director of the shaw yong, unlike traditional melting technology, nano knife is not using the "hot" or "cold" effect on physical ablation, but by high voltage pulse current disrupt the cell membrane of tumor cells directly, can make the tumor cell death, and can well protect the blood vessels around the nerve, bile duct, pancreatic duct and other important organization are not affected. At the same time, it has the characteristics of small trauma, mild pain and quick recovery.

According to the introduction, nano-knife technology was approved by the European Union as early as March 2010, and was approved by the us FDA for clinical treatment in October 2011, and was officially introduced into China at the end of June. It has been carried out in more than 100 central cancer hospitals around the world, and has been treated for more than 6,000 surgical patients. Its safety and effectiveness have been recognized worldwide.

The university of louisville in Kentucky, according to a study according to the data, the six surgery center and has a history of locally advanced pancreatic cancer, compared to patients on the control of the nanometer technology knife can prolongs the median survival 2 times.