Amaprotheni asanda kutholwa asekela ukucwiliswa okusebenzayo komhlaba ongavamile

Umthombo: Izimayini

Ephepheni elisanda kushicilelwa ku-Journal of Biological Chemistry, abacwaningi e-Eth Zurich bachaza ukutholwa kweLanpepsy, amaprotheni ahlanganisa izinto ezithile ze-lanthanides - noma izinto zomhlaba ezingandile - futhi zibandlulula kwezinye izimbiwana nezinsimbi.

Ngenxa yokufana kwabo namanye ama-ion wensimbi, ukuhlanzwa kwe-ree kusuka emvelweni kuyinto ebomvu futhi kwezomnotho kuphela ezindaweni ezimbalwa. Ukwazi lokhu, ososayensi banquma ukuhlola izinto eziphilayo ngokucaciswa okuphezulu okuhlanganisiwe kweLanthanides njengezindlela ezinganikeza indlela eya phambili.

Isinyathelo sokuqala kwakuwukubukeza izifundo ezedlule eziphakamisa ukuthi imvelo iveze amaprotheni ahlukahlukene noma ama-molecule amancane e-scavenge lanthanides. Amanye amaqembu okucwaninga athole ukuthi ama-bacterium athile, ama-methylotrophs aguqula i-methane noma i-methanol, enama-enzyme adinga ama-lanthanides kumasayithi abo asebenzayo. Kusukela kwatholwa okokuqala kulo mkhakha, ukukhonjwa kanye nokubonakala kwamaprotheni ahilelekile ekuzwaneni, ukushesha, kanye nokusetshenziswa kwama-lanthanides, sekuphenduke umkhakha wocwaningo oluvelayo.

Ukuhlonza abalingisi benoveli eLanthanome, uJetro hemmann kanye noPhilipp KiPhili kanye nelabhoratri nelabhorethri kaDetlef Günther e-D-Chab, bafundela impendulo ye-LANTHANIDE ye-Orthanide Metylobacillus FlagelLellatus.

Ngokuqhathanisa ama-protereome of amaseli akhule ebukhoneni kanye nokungabikho kweLanthanum, bathola amaprotheni amaningana ahlobene kakhulu nokusetshenziswa kweLanthanide.

Phakathi kwazo kwakukhona amaprotheni amancane omsebenzi ongaziwa, iqembu manje eliqanjwe ngalo uLanpepsy. Emihlosweni we-vitro wamaprotheni aveze amasayithi abophayo e-lanthanides anokucaciswa okuphezulu kweLanthanum ngaphezulu kwe-calcium eyikhaliphile.

ILanpepsy iyakwazi ukucebisa ama-lanthanides kusuka kusisombululo futhi ngaleyo ndlela ibambe amathuba okuthuthuka kwezinqubo ze-bioinspired zokuhlanzwa okuzinzile komhlaba ongavamile.

---

Isikhathi sePosi: Mar-08-2023