Iprotheyini esandula ukufunyanwa ixhasa ukucocwa okusebenzayo kweRare Earth
Iprotheyini esandula ukufunyanwa ixhasa ukucocwa okusebenzayo kweRare Earth Kwiphepha lamva nje elipapashwe kwiJenali yeBiological Chemistry, abaphandi base-ETH Zurich bachaza ukufunyanwa kwe-lanpepsy, iprotheni ebopha ngokuthe ngqo i-lanthanides - okanye izinto ezinqabileyo zomhlaba - kwaye iyabacalula kwezinye iiminerali kunye nesinyithi. Ngenxa yokufana kwazo nezinye ii-ion zentsimbi, ukucocwa kwe-REE kokusingqongileyo kunzima kwaye kunoqoqosho kuphela kwiindawo ezimbalwa.Ukwazi oku, izazinzulu ziye zagqiba ekubeni zihlolisise izinto zebhayoloji ezinezibophelelo eziphezulu zokubopha i-lanthanides njengeendlela ezinokunika indlela eya phambili. Inyathelo lokuqala yayikukuphonononga izifundo zangaphambili ezibonisa ukuba indalo iye yavela kwiiprotheyini ezahlukeneyo okanye iimolekyuli ezincinci ukuze zikhuphe i-lanthanides.Amanye amaqela ophando afumene ukuba iibhaktheriya ezithile, i-methylotrophs eziguqula i-methane okanye i-methanol, zinee-enzyme ezifuna i-lanthanides kwiindawo zabo ezisebenzayo.Ukusukela oko kwafunyaniswa okokuqala kule ntsimi, ukuchongwa kunye nokubonakaliswa kweeprotheyini ezibandakanyekayo ekuboneni, ekuthatheni nasekusetyenzisweni kwe-lanthanides, kuye kwaba yinkalo yophando evelayo. Ukuchonga abadlali benoveli kwi-lanthanome, u-Jethro Hemmann kunye no-Philipp Keller kunye nabadibanisi abavela kwi-D-BIOL kunye nebhubhoratri ye-Detlef Günther e-D-CHAB, bafunde impendulo ye-lanthanide yesibophelelo se-methylotroph Methylobacillus flagellatus. Ngokuthelekisa iproteome yeeseli ezikhule phambi kobukho kunye nokungabikho kwe-lanthanum, bafumene iiprotheni ezininzi ezingahambelani ngaphambili nokusetyenziswa kwe-lanthanide. Phakathi kwazo kwakukho iprotein encinci yemisebenzi engaziwayo, iqela ngoku ebizwa ngokuba yi-lanpepsy.Ukubonakaliswa kwe-in vitro yeprotheyini kubonise iindawo ezibophelelayo ze-lanthanides ezineenkcukacha eziphezulu ze-lanthanum ngaphezu kwekhemikhali efana ne-calcium. I-Lanpepsy iyakwazi ukutyebisa i-lanthanides kwisisombululo kwaye ibambe amandla okuphuhliswa kweenkqubo ze-bioinspired zokuhlanjululwa okuzinzileyo komhlaba onqabileyo.
Ixesha lokuposa: Mar-08-2023